IWP-2


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-13912-5MG 5 mg 67,00 50,30 Add
HY-13912-10MG 10 mg 106,00 79,50 Add
HY-13912-25MG 25 mg 216,00 162,00 Add
HY-13912-50MG 50 mg 348,00 261,00 Add
HY-13912-100MG 100 mg 544,00 408,00 Add
HY-13912-S-1ST Sample   Inquire

* CHF, excl. 7.7% VAT and shipping costs


Product Description

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IWP-2 is an inhibitor of Wnt processing and secretion with an IC50 of 27 nM. IWP-2 targets the membrane-bound O-acyltransferase porcupine (Porcn) and thus preventing a crucial Wnt ligand palmitoylation. IWP-2 is also an ATP-competitive CK1δ inhibitor with an IC50 of 40 nM for the gatekeeper mutant M82FCK1δ.

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Stem Cell/Wnt, Cell Cycle/DNA Damage
Format Solubility: DMF : 12.5 mg/mL (26.79 mM; ultrasonic and warming and heat to 60°C) ; DMSO : 2 mg/mL (4.29 mM; Need ultr...
Grade Clinical information: No Development Reported
Purity 95.68%
Molecular Formula C22H18N4O2S3
Molecular Weight 466.6
CAS-Number 686770-61-6
Storage Conditions Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room temperature
Material Safety Data Sheet Download PDF