Talfirastide
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-12403-5MG | 5 mg | 97,00 | Add | |
| HY-12403-1ML | 10mM/1mL | 146,00 | Add | |
| HY-12403-10MG | 10 mg | 147,00 | Add | |
| HY-12403-25MG | 25 mg | 213,00 | Add | |
| HY-12403-50MG | 50 mg | 365,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC50=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity [1][2][3].
| Category | Peptide |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Inflammation/Immunology, Cardiovascular Disease, Endocrinology, GPCR/G Protein,Metabolic Enzyme/Protease |
| Format | Solubility: H2O : ≥ 30.2 mg/mL |
| Grade | Clinical information: No Development Reported |
| Purity | 99.91% |
| Molecular Formula | C41H62N12O11 |
| Molecular Weight | 899 |
| CAS-Number | 51833-78-4 |
| Storage Conditions | -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
