UbE3A (E6AP)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
K1411-50uG | 50 µg | 517,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
UbE3A (also called E6AP) is a 100 kDa HECT (homologous to E6AP carboxyl terminus) domain ubiquitin ligase containing two E2 binding sites for UbcH7 and UbcH8. UbE3A was found to bind to the human papillomavirus (HPV) oncoprotein E6 and mediate ubiquitination of p53. A frameshift mutation in the UbE3A gene leads to loss of function and causes Angelman Syndrome. This product is made from GST-UbE3A (catalog # K1410) by removal of the N-terminal GST tag.
Category | Enzyme/Substrate |
Supplier | UBPBio |
Regulatory Status | RUO |
Species Specificity | Hu |
Format | 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol |
Storage Conditions | -80°C |
Disclaimer | Shipped on dry ice - extra freight charge will occur |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.ubpbio.com |
Shipping Details | Dry ice |
Material Safety Data Sheet | Download PDF |