6xHis-USP16


Catalog Number Pack Size List Price* Quantity
H6600-25uG 25 µg 517,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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USP16 is an active deubiquitinating enzyme (DUB) encoded on chromosome 21, trisomy of which causes Down’s syndrome (DS). USP16 is a phosphoprotein, phosphorylation of USP16 controls its cellular localization, but no effect on its DUB activity. USP16 deubiquitinates histone 2A (H2A), through which USP16 might regulate gene expression and cell cycle progression. Increased USP16 protein levels in people with DS might contribute to the development of certain phenotypes of DS.

Category Enzyme/Substrate
Supplier UBPBio
Regulatory Status RUO
Species Specificity Hu
Format 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
Storage Conditions -80°C
Disclaimer Shipped on dry ice - extra freight charge will occur
Tech. Data Sheet View datasheet
Link To Supplier http://www.ubpbio.com
Shipping Details Dry ice
Material Safety Data Sheet Download PDF