BMS-984923
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-122559-10MG | 10 mg | Inquire | ||
| HY-122559-5MG | 5 mg | Inquire |
* CHF, excl. 7.7% VAT and shipping costs
Product Description
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BMS-984923, a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling.
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Neurological Disease, GPCR/G Protein, Neuronal Signaling |
| Format | Solubility: DMSO : 100 mg/mL (266.79 mM; Need ultrasonic) |
| Grade | Clinical information: Phase 1 |
| Purity | 99.94% |
| Molecular Formula | C22H15ClN2O2 |
| Molecular Weight | 374.82 |
| CAS-Number | 1375752-78-5 |
| Storage Conditions | Powder -20°C 3 years; In solvent -80°C 6 months, -20°C 1 month |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room temperature |
| Material Safety Data Sheet | Download PDF |
