BMS-984923
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-122559-5MG | 5 mg | 710,00 | Add | |
HY-122559-1ML | 10mM/1mL | 780,00 | Add | |
HY-122559-10MG | 10 mg | 1'153,00 | Add | |
HY-122559-25MG | 25 mg | 2'357,00 | Add | |
HY-122559-50MG | 50 mg | 3'814,00 | Add | |
HY-122559-100MG | 100 mg | 6'094,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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BMS-984923, a potent mGluR5 silent allosteric modulator (SAM), with exquisite binding affinity (Ki = 0.6 nM), exhibits good oral bioavailability and BBB penetration. BMS-984923 potently inhibits the PrPC-mGluR5 interaction and prevents pathological Aβo signaling without affecting physiological glutamate signaling[1][2].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Neurological Disease, GPCR/G Protein,Neuronal Signaling |
Format | Solubility: DMSO : 50 mg/mL (ultrasonic) |
Grade | Clinical information: Phase 1 |
Purity | 99.94% |
Molecular Formula | C22H15ClN2O2 |
Molecular Weight | 374.82 |
CAS-Number | 1375752-78-5 |
Storage Conditions | -20°C, 3 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Blue Ice |
Material Safety Data Sheet | Download PDF |