CD40L/CD154/TRAP, Human (HEK293, Tag free)


Catalog Number Pack Size List Price* Quantity
HY-P70609-10uG 10 μg 153,00 Add
HY-P70609-50uG 50 μg 432,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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CD40L (CD154; TRAP) is a ligand to CD40/TNFRSF5, acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1]. CD40L is specifically expressed on activated CD4+ T-lymphocytes and involves in activation of NF-κB/MAPK pathway[2][3]. CD40L also involves in B cell differentiation, maturation, and apoptosis[4]. CD40L in human, cleaved into 2 chains of membrane form (1-261 a.a.) and soluble form (113-261 a.a.) which serves as a ligand for integrins (ITGA5:ITGB1 and ITGAV:ITGB3). GMP CD40L/CD154/TRAP Protein, Human (HEK293) has a total length of 149 amino acids (M113-L261), is expressed in HEK392 cells under GMP standard with tag free.

Category Protein
Supplier MedChem Express
Regulatory Status RUO
Genebank 959(Gene_ID)P29965 (M113-L261)(Access...
Purity 96.75%
Molecular Weight 1618
Storage Conditions Stored at -20°C for 2 years
Link To Supplier http://www.medchemexpress.com
Shipping Details Blue Ice
Material Safety Data Sheet Download PDF