Zabedosertib
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-139374-5MG | 5 mg | 241,00 | Add | |
| HY-139374-1ML | 10mM/1mL | 265,00 | Add | |
| HY-139374-10MG | 10 mg | 393,00 | Add | |
| HY-139374-25MG | 25 mg | 773,00 | Add | |
| HY-139374-50MG | 50 mg | 1'230,00 | Add | |
| HY-139374-100MG | 100 mg | 1'977,00 | Add | |
| HY-139374-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Inflammation/Immunology, Immunology/Inflammation |
| Format | Solubility: DMSO : 125 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: Phase 2 |
| Purity | 99.12% |
| Molecular Formula | C20H21F3N4O4S |
| Molecular Weight | 470.47 |
| CAS-Number | 1931994-81-8 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
