SKLB325


Catalog Number Pack Size List Price* Quantity
HY-139782-5MG 5 mg 456,00 Add
HY-139782-1ML 10mM/1mL 501,00 Add
HY-139782-10MG 10 mg 673,00 Add
HY-139782-25MG 25 mg 1'255,00 Add
HY-139782-50MG 50 mg 1'812,00 Add
HY-139782-100MG 100 mg 2'484,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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SKLB325 is a Jumonji domain-containing 6 (JMJD6) inhibitor with a binding affinity (KD) value of 0.755 μM, and the IC50 value of 0.7797 μM. SKLB325 exhibits antitumor effects on ovarian cancer in vivo and in vitro. SKLB325 induces apoptosis[1]. SKLB325 exhibits remarkable antitumor efficacy in renal cell carcinoma (RCC) [2].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,Epigenetics
Format Solubility: DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Grade Clinical information: No Development Reported
Purity 99.79%
Molecular Formula C12H12N4O2
Molecular Weight 244.25
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF