CCT367766 (formic)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-122653A-5MG | 5 mg | 660,00 | Add | |
| HY-122653A-10MG | 10 mg | 1'053,00 | Add | |
| HY-122653A-25MG | 25 mg | 2'103,00 | Add | |
| HY-122653A-50MG | 50 mg | 3'357,00 | Add | |
| HY-122653A-100MG | 100 mg | 5'333,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity for the CRBN-DDB1 complex with an IC50 value of 490 nM. CCT367766 formic reveals a good affinity for the recombinant pirin and CRBN with Kd values of 55 nM and 120 nM, respectively. CCT367766 formic provides a potential chemical tool to study a largely unexplored protein[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, PROTAC |
| Format | Solubility: DMSO : ≥ 250 mg/mL |
| Grade | Clinical information: No Development Reported |
| Purity | 98.02% |
| Molecular Formula | C50H50ClN7O13 |
| Molecular Weight | 992.42 |
| Storage Conditions | -20°C (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
