FA16


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HY-151964-1ST Get quote   Inquire

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Product Description

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FA16 is a specific ferroptosis inducer (IC50=1.26 μM; HT1080 cells) with metabolic stability, is the derivate of 2-(trifluoromethyl)benzimidazole. FA16 acts by inhibiting cystine/glutamate antiporter (system Xc-), which mediates the exchange of intracellular glutamate and extracellular cystine. FA16 significantly inhibits tumor growth in the HepG2 xenograft model[1].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis
Format Solubility: 10 mM in DMSO
Grade Clinical information: No Development Reported
Molecular Formula C22H25F3N4O2S
Molecular Weight 466.52
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room temperature
Material Safety Data Sheet Download PDF