Losartan-d4 (carboxylic acid)
| Catalog Number | Pack Size | List Price* | Promo Price* | Quantity | |
|---|---|---|---|---|---|
| HY-12765S-1MG | 1 mg | 292,00 | 181,10 | Add | |
| HY-12765S-5MG | 5 mg | 1'067,00 | 661,60 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Promotion runs until 31.12.2026Best price guarantee – we offer you the lowest price in Switzerland. Please contact us for a quote if needed.
E-3174 D4; EXP-3174 D4
Losartan-d4 carboxylic acid (E-3174-d4) is the deuterium labeled Losartan Carboxylic Acid (HY-12765) . Losartan Carboxylic Acid (E-3174) , an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1, respectively. Losartan Carboxylic Acid blocks the angiotensin II-induced responses in vascular smoothmuscle cells (VSMC) . Losartan Carboxylic Acid elevates plasma renin activities and reduces mean arterial pressure.
| Category | Biochemicals |
| Supplier | MedChem Express |
| Application | Isotope-labeled compound |
| Regulatory Status | RUO |
| Research Field | Cardiovascular Disease; Endocrinology; Cancer |
| Format | Solubility: 10 mM in DMSO;DMSO : ≥ 250mg/mL |
| Grade | Clinical information: No Development Reported |
| Purity | 98.09% |
| Molecular Formula | C22H17D4ClN6O2 |
| Molecular Weight | 440.92 |
| CAS-Number | 1246820-62-1 |
| Storage Conditions | -20°C, 3 years (Powder) |
| Disclaimer | Deuterated products takes approx 1 week longer delivery time |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
