Ruxolitinib
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-50856-5MG | 5 mg | 105,00 | Add | |
| HY-50856-1ML | 10mM/1mL | 114,00 | Add | |
| HY-50856-10MG | 10 mg | 120,00 | Add | |
| HY-50856-50MG | 50 mg | 196,00 | Add | |
| HY-50856-100MG | 100 mg | 257,00 | Add | |
| HY-50856-200MG | 200 mg | 409,00 | Add | |
| HY-50856-500MG | 500 mg | 713,00 | Add | |
| HY-50856-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Ruxolitinib (INCB18424) is a potent and selective JAK1/2 inhibitor with IC50s of 3.3 nM and 2.8 nM in cell-free assays, and has 130-fold selectivity for JAK1/2 over JAK3[1]. Ruxolitinib induces autophagy and kills tumor cells through toxic mitophagy[3].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Autophagy,Epigenetics,JAK/STAT Signaling,Protein Tyrosine Kinase/RTK,Stem Cell/Wnt |
| Format | Solubility: H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: Launched |
| Purity | 99.99% |
| Molecular Formula | C17H18N6 |
| Molecular Weight | 306.37 |
| CAS-Number | 941678-49-5 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
