Regorafenib


Catalog Number Pack Size List Price* Quantity
HY-10331-5MG 5 mg 61,00 Add
HY-10331-10MG 10 mg 89,00 Add
HY-10331-1ML 10mM/1mL 97,00 Add
HY-10331-50MG 50 mg 165,00 Add
HY-10331-100MG 100 mg 241,00 Add
HY-10331-500MG 500 mg 508,00 Add
HY-10331-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1, respectively. Regorafenib shows very robust antitumor and antiangiogenic activity[1].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Autophagy,MAPK/ERK Pathway,Protein Tyrosine Kinase/RTK
Format Solubility: DMSO : 125 mg/mL (ultrasonic)
Grade Clinical information: Launched
Purity 99.93%
Molecular Formula C21H15ClF4N4O3
Molecular Weight 482.82
CAS-Number 755037-03-7
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF