Danoprevir
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-10238-5MG | 5 mg | 229,00 | Add | |
HY-10238-1ML | 10mM/1mL | 361,00 | Add | |
HY-10238-10MG | 10 mg | 393,00 | Add | |
HY-10238-50MG | 50 mg | 1'343,00 | Add | |
HY-10238-100MG | 100 mg | 2'103,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases (IC50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 (IC50s=0.2-0.4 nM) as well as 2b and 3a (IC50s=1.6, 3.5 nM)[1][2]. Danoprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 0.05 μM[3].
Category | Antibiotics |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Infection, Anti-infection,Metabolic Enzyme/Protease |
Format | Solubility: DMSO : ≥ 100 mg/mL |
Grade | Clinical information: Launched |
Purity | 99.69% |
Molecular Formula | C35H46FN5O9S |
Molecular Weight | 731.83 |
CAS-Number | 850876-88-9 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |