Vps34-IN-1


Catalog Number Pack Size List Price* Quantity
HY-12795-5MG 5 mg 153,00 Add
HY-12795-1ML 10mM/1mL 167,00 Add
HY-12795-10MG 10 mg 236,00 Add
HY-12795-50MG 50 mg 641,00 Add
HY-12795-100MG 100 mg 919,00 Add
HY-12795-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Vps34-IN-1 is a potent and selective inhibitor of class III Vps34 PI3K. Vps34-IN-1 inhibits phosphorylation of PtdIns by recombinant insect cell expressed Vps34-Vps15 complex with an IC50 of ~25 nM. Vps34-IN-1 can suppress SGK3 activation by reducing PtdIns(3)P levels via lowering phosphorylation of T-loop and hydrophobic motifs. Vps34-IN-1 modulates autophagy[1][2][3].

Category Inhibitor
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Autophagy,PI3K/Akt/mTOR
Format Solubility: DMSO : ≥ 31 mg/mL
Grade Clinical information: No Development Reported
Purity 99.56%
Molecular Formula C21H24ClN7O
Molecular Weight 425.91
CAS-Number 1383716-33-3
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF