Vps34-IN-1
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-12795-5MG | 5 mg | 153,00 | Add | |
HY-12795-1ML | 10mM/1mL | 167,00 | Add | |
HY-12795-10MG | 10 mg | 236,00 | Add | |
HY-12795-50MG | 50 mg | 641,00 | Add | |
HY-12795-100MG | 100 mg | 919,00 | Add | |
HY-12795-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Vps34-IN-1 is a potent and selective inhibitor of class III Vps34 PI3K. Vps34-IN-1 inhibits phosphorylation of PtdIns by recombinant insect cell expressed Vps34-Vps15 complex with an IC50 of ~25 nM. Vps34-IN-1 can suppress SGK3 activation by reducing PtdIns(3)P levels via lowering phosphorylation of T-loop and hydrophobic motifs. Vps34-IN-1 modulates autophagy[1][2][3].
Category | Inhibitor |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Autophagy,PI3K/Akt/mTOR |
Format | Solubility: DMSO : ≥ 31 mg/mL |
Grade | Clinical information: No Development Reported |
Purity | 99.56% |
Molecular Formula | C21H24ClN7O |
Molecular Weight | 425.91 |
CAS-Number | 1383716-33-3 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |