Tamoxifen
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-13757A-100MG | 100 mg | 46,00 | Add | |
| HY-13757A-200MG | 200 mg | 57,00 | Add | |
| HY-13757A-500MG | 500 mg | 89,00 | Add | |
| HY-13757A-1ML | 10mM/1mL | 97,00 | Add | |
| HY-13757A-1G | 1 g | 119,00 | Add | |
| HY-13757A-5G | 5 g | 378,00 | Add | |
| HY-13757A-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Tamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[1][2][3]. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively[5]. Tamoxifen activates autophagy and induces apoptosis[4]. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse[6].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,Autophagy,Cell Cycle/DNA Damage,Metabolic Enzyme/Protease,Vitamin D Related/Nuclear Receptor |
| Format | Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C);Ethanol : 50 mg/mL (ultrasonic) |
| Grade | Clinical information: Launched |
| Purity | 99.92% |
| Molecular Formula | C26H29NO |
| Molecular Weight | 371.51 |
| CAS-Number | 10540-29-1 |
| Storage Conditions | 4°C (Powder, protect from light) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
