Birinapant
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-16591-5MG | 5 mg | 120,00 | Add | |
| HY-16591-1ML | 10mM/1mL | 176,00 | Add | |
| HY-16591-10MG | 10 mg | 196,00 | Add | |
| HY-16591-50MG | 50 mg | 440,00 | Add | |
| HY-16591-100MG | 100 mg | 773,00 | Add | |
| HY-16591-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Best price guarantee – we offer you the lowest price in Switzerland. Please contact us for a quote if needed.
Birinapant (TL32711), a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1 with Kds of 45 nM and less than 1 nM, respectively. Birinapant (TL32711) induces the autoubiquitylation and proteasomal degradation of cIAP1 and cIAP2 in intact cells, which results in formation of a RIPK1: caspase-8 complex, caspase-8 activation, and induction of tumor cell death. Birinapant (TL32711) targets TRAF2-associated cIAPs and abrogates TNF-induced NF-κB activation.
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Anti-infection,Apoptosis |
| Format | Solubility: DMSO : 125 mg/mL (ultrasonic) |
| Grade | Clinical information: Phase 2 |
| Purity | 99.7% |
| Molecular Formula | C42H56F2N8O6 |
| Molecular Weight | 806.94 |
| CAS-Number | 1260251-31-7 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
