DAPT
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-13027-5MG | 5 mg | 98,00 | Add | |
| HY-13027-1ML | 10mM/1mL | 107,00 | Add | |
| HY-13027-10MG | 10 mg | 159,00 | Add | |
| HY-13027-50MG | 50 mg | 463,00 | Add | |
| HY-13027-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Inflammation/Immunology, Neurological Disease, Apoptosis,Autophagy,Neuronal Signaling,Stem Cell/Wnt |
| Format | Solubility: DMSO : 62.5 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 99.91% |
| Molecular Formula | C23H26F2N2O4 |
| Molecular Weight | 432.46 |
| CAS-Number | 208255-80-5 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
