Niraparib
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-10619-5MG | 5 mg | 102,00 | Add | |
HY-10619-1ML | 10mM/1mL | 111,00 | Add | |
HY-10619-10MG | 10 mg | 140,00 | Add | |
HY-10619-50MG | 50 mg | 241,00 | Add | |
HY-10619-100MG | 100 mg | 368,00 | Add | |
HY-10619-500MG | 500 mg | 875,00 | Add | |
HY-10619-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Apoptosis,Cell Cycle/DNA Damage,Epigenetics |
Format | Solubility: DMSO : 25 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C) |
Grade | Clinical information: Launched |
Purity | 99.96% |
Molecular Formula | C19H20N4O |
Molecular Weight | 320.39 |
CAS-Number | 1038915-60-4 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |