Niraparib


Catalog Number Pack Size List Price* Quantity
HY-10619-5MG 5 mg 102,00 Add
HY-10619-1ML 10mM/1mL 111,00 Add
HY-10619-10MG 10 mg 140,00 Add
HY-10619-50MG 50 mg 241,00 Add
HY-10619-100MG 100 mg 368,00 Add
HY-10619-500MG 500 mg 875,00 Add
HY-10619-S-1ST Sample   Inquire

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity[1][2][3].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer, Apoptosis,Cell Cycle/DNA Damage,Epigenetics
Format Solubility: DMSO : 25 mg/mL (ultrasonic);H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
Grade Clinical information: Launched
Purity 99.96%
Molecular Formula C19H20N4O
Molecular Weight 320.39
CAS-Number 1038915-60-4
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF