Sorafenib
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-10201-100MG | 100 mg | 89,00 | Add | |
HY-10201-1ML | 10mM/1mL | 97,00 | Add | |
HY-10201-1G | 1 g | 173,00 | Add | |
HY-10201-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Sorafenib (Bay 43-9006) is a potent and orally active Raf inhibitor with IC50s of 6 nM and 20 nM for Raf-1 and B-Raf, respectively. Sorafenib is a multikinase inhibitor with IC50s of 90 nM, 15 nM, 20 nM, 57 nM and 58 nM for VEGFR2, VEGFR3, PDGFRβ, FLT3 and c-Kit, respectively. Sorafenib induces autophagy and apoptosis. Sorafenib has anti-tumor activity. Sorafenib is a ferroptosis activator[1].
Category | Biochemicals |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cancer, Apoptosis,Autophagy,MAPK/ERK Pathway,Protein Tyrosine Kinase/RTK |
Format | Solubility: DMSO : ≥ 45 mg/mL |
Grade | Clinical information: Launched |
Purity | 99.92% |
Molecular Formula | C21H16ClF3N4O3 |
Molecular Weight | 464.83 |
CAS-Number | 284461-73-0 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |