GDC-0068(RG7440)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| F6170-5MG | 5 mg | 96,00 | Add | |
| F6171-25MG | 25 mg | 301,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Please inquire a quote for two or more UBPBio products
GDC-0068 (RG7440 or Ipatasertib) is a novel, ATP-competitive Akt1/2/3 inhibitor with IC50 values of 5 nM, 18 nM and 8 nM, respectively. GDC-0068 selectively inhibits cell cycle progression and viability of cancer cell lines driven by PI3K/Akt signaling pathway, including those with defects of the tumor suppressor PTEN, oncogenic mutations in PIK3CA, and amplification of HER2. GDC-0068 blocks the phosphorylation of multiple downstream targets of Akt in human cancer cell lines.
| Category | Inhibitor |
| Supplier | UBPBio |
| Regulatory Status | RUO |
| Format | Powder; no buffer |
| CAS-Number | 1001264-89-6 |
| Storage Conditions | -20°C |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.ubpbio.com |
| Shipping Details | Ambient temp. |
| Material Safety Data Sheet | Download PDF |
