Ubiquitin (K63R)


Catalog Number Pack Size List Price* Quantity
E1680-1MG 1 mg 353,00 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

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Ubiquitin (Ub) is a 76 amino acid protein widely expressed in the cytoplasmic and nucleus of cells. Ub is posttranslationally conjugated to proteins by the E1, E2, E3 protein ubiquitination cascade. Ub can be conjugated on proteins as monoUb or polyUb chains. Protein ubiquitination plays both proteolytic and nonproteolytic functions. Usually, polyubiquitinated proteins are targeted to the 26S proteasome for proteolysis. Typical concentration to support in vitro ubiquitination is 50-100 µM. In Ub(K63R), lysine 63 was substituted with an arginine, thereby it cannot form lysine 63-linked polyubiquitin chains.

Category Protein
Supplier UBPBio
Regulatory Status RUO
Species Specificity Hu
Format 20 mM Tris, 150 mM NaCl, 2 mM BME, 10% Glycerol
Storage Conditions -80°C
Disclaimer Shipped on dry ice - extra freight charge will occur
Tech. Data Sheet View datasheet
Link To Supplier http://www.ubpbio.com
Shipping Details Dry ice
Material Safety Data Sheet Download PDF