BMP-7, Human
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-P7008-10uG | 10 μg | 368,00 | Add | |
HY-P7008-50uG | 50 μg | 1'077,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Bone morphogenetic protein 7 (BMP-7) is a polymorphic ligand protein belonging to the TGFβ family. BMP-7 is involved in regulating the proliferation, invasion and migration of cancer cells and is associated with a variety of human tumors[1]. BMP-7 binds ALK2 or ACVR2A/BMPR2 excitation signal, which is terminated by SMADs regulation[2]. BMP-7 is involved in the BMP-7-SMad1/5/9 signaling pathway, which is associated with the epithelial-mesenchymal transition (EMT) process[1]. BMP-7 also eliminates vascular inflammation, maintains vascular integrity[3], reduces vascular calcification, and stimulates in situ phosphate ossification deposition[4]. The total length of human BMP-7 protein is 431 amino acids (M1-H431), with 4 glycosylation domains. BMP-7 Protein, Human has a total length of 139 amino acids (S293-H431), is expressed in E. coli cells.
Category | Protein |
Supplier | MedChem Express |
Regulatory Status | RUO |
Genebank | 655(Gene_ID)P18075 (S293-H431)(Access... |
Purity | 95% |
Molecular Weight | 15.7 |
Storage Conditions | Stored at -20°C for 2 years |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Blue Ice |
Material Safety Data Sheet | Download PDF |