PROTAC Bcl2 degrader-1
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-125876-1MG | 1 mg | 710,00 | Add | |
| HY-125876-5MG | 5 mg | 1'255,00 | Add | |
| HY-125876-10MG | 10 mg | 1'914,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Apoptosis,PROTAC |
| Format | Solubility: DMSO : 25 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.78% |
| Molecular Formula | C45H45BrN6O10S |
| Molecular Weight | 941.84 |
| CAS-Number | 2378801-85-3 |
| Storage Conditions | -20°C (Powder, stored under nitrogen) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
