PMX-53
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-106178-5MG | 5 mg | 317,00 | Add | |
| HY-106178-1ML | 10mM/1mL | 500,00 | Add | |
| HY-106178-10MG | 10 mg | 508,00 | Add | |
| HY-106178-25MG | 25 mg | 1'065,00 | Add | |
| HY-106178-50MG | 50 mg | 1'686,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC50 of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects[1][2][3][4][5][6].
| Category | Peptide |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Inflammation/Immunology, Cardiovascular Disease, Immunology/Inflammation |
| Format | Solubility: DMSO : 200 mg/mL (ultrasonic);H2O : 2.5 mg/mL (ultrasonic;warming;heat to 60°C) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.6% |
| Molecular Formula | C47H65N11O7 |
| Molecular Weight | 896.09 |
| CAS-Number | 219639-75-5 |
| Storage Conditions | -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
