Metformin-d6 (hydrochloride)
| Catalog Number | Pack Size | List Price* | Promo Price* | Quantity | |
|---|---|---|---|---|---|
| HY-110228-1MG | 1 mg | 169,00 | 109,90 | Add | |
| HY-110228-5MG | 5 mg | 537,00 | 349,10 | Add | |
| HY-110228-10MG | 10 mg | 822,00 | 534,30 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Promotion runs until 31.12.2025Best price guarantee – we offer you the lowest price in Switzerland. Please contact us for a quote if needed.
1,1-Dimethylbiguanide-d6 (hydrochloride)
Metformin-d6 hydrochloride is a deuterium labeled Metformin hydrochloride. Metformin hydrochloride inhibits the mitochondrial respiratory chain in the liver, leading to AMPK activation and enhancing insulin sensitivity, and can be used in the study of type 2 diabetes. Metformin hydrochloride also inhibits liver oxidative stress, nitrosative stress, inflammation, and apoptosis caused by liver ischemia/reperfusion injury. In addition, metformin hydrochloride regulates the expression of autophagy-related proteins by activating AMPK and inhibiting the mTOR signaling pathway, thereby inducing tumor cell autophagy and inhibiting the growth of renal cell carcinoma in vitro and in vivo[1].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Application | Isotope-labeled compound |
| Regulatory Status | RUO |
| Research Field | Metabolic Disease, Cardiovascular Disease |
| Format | Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) ;H2O : 50 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.79% |
| Molecular Formula | C4H6D6ClN5 |
| Molecular Weight | 171.66 |
| CAS-Number | 1185166-01-1 |
| Storage Conditions | 4°C (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
