UT-34
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-136242-5MG | 5 mg | 204,00 | Add | |
| HY-136242-1ML | 10mM/1mL | 222,00 | Add | |
| HY-136242-10MG | 10 mg | 330,00 | Add | |
| HY-136242-25MG | 25 mg | 710,00 | Add | |
| HY-136242-50MG | 50 mg | 1'217,00 | Add | |
| HY-136242-100MG | 100 mg | 1'977,00 | Add | |
| HY-136242-S-1ST | Sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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UT-34 is a potent, selective and orally active second-generation pan-androgen receptor (AR) antagonist and degrader with IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively. UT-34 binds to ligand-binding domain (LBD) and function-1 (AF-1) domains and requires ubiquitin proteasome pathway to degrade the AR. UT-34 has anti-prostate cancer efficacy[1][2].
| Category | Biochemicals |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Endocrinology, Vitamin D Related/Nuclear Receptor |
| Format | Solubility: DMSO : 250 mg/mL (ultrasonic) |
| Grade | Clinical information: No Development Reported |
| Purity | 98.01% |
| Molecular Formula | C15H12F4N4O2 |
| Molecular Weight | 356.27 |
| CAS-Number | 2168525-92-4 |
| Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Room Temperature |
| Material Safety Data Sheet | Download PDF |
