Transthyretin 56-61, amyloid specific (mouse monoclonal)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| AS16 3113 | 100 µg | 479,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Specifically reactive to the amyloid form of human Transthyretin. Epitope mapped to residue 56-61 which remains buried within the native fold of transthyretin but becomes exposed within its amyloid form.It has been suggested that that two distinct mechanisms of TTR-amyloidosis exists. The first, most common seen in wild type TTR Amyloidosis, consists of the full length TTR. Whereas the other type of amyloidosis mainly consists of the C-terminal region of the protein and is more common in mutant versions of TTR. Mouse IgG1 Anti-Transthyretin 56-61 (Amyloid Specific) epitope is located at the C-terminal strand of cleaved TTR and is suitable to detect amyloid formation derived from the C-terminal.
| Category | Antibody |
| Supplier | Agrisera |
| Application | EL, IHC, WB |
| Regulatory Status | RUO |
| Research Field | Pathology, Alzheimer's disease |
| Species Specificity | Hu |
| Immunogen | Recombinant protein corresponding to the Human wild type Transthyretin. GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNP... |
| Host | Ms |
| Isotype | IgG1 |
| Crossreactivity | Hu |
| Clonality | Mab |
| Format | Lyophilized |
| Working Dilution | 1:1000 (ELISA), 1:500 (IHC), 1:1000 (WB) |
| Purity | Affinity purified in PBS pH 7.4. |
| Storage Conditions | Store lyophilized/reconstituted at 4°C, Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or... |
| References | Antibodies cited in scientific publications |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.agrisera.com |
| Material Safety Data Sheet | Download PDF |
