Angiotensin II human (TFA)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-13948B-5MG | 5 mg | 74,00 | Add | |
| HY-13948B-10MG | 10 mg | 109,00 | Add | |
| HY-13948B-50MG | 50 mg | 393,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Angiotensin II human (Angiotensin II) TFA is a vasoconstrictor and a major bioactive peptide of the renin/angiotensin system. Angiotensin II human TFA plays a central role in regulating human blood pressure, which is mainly mediated by interactions between Angiotensin II and the G-protein-coupled receptors (GPCRs) Angiotensin II type 1 receptor (AT1R) and Angiotensin II type 2 receptor (AT2R). Angiotensin II human TFA stimulates sympathetic nervous stimulation, increases aldosterone biosynthesis and renal actions. Angiotensin II human TFA induces growth of vascular smooth muscle cells, increases collagen type I and III synthesis in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. Angiotensin II human TFA also induces apoptosis. Angiotensin II human TFA induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway[1][2][3][4].
| Category | Peptide |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Cancer, Endocrinology, Cardiovascular Disease, Apoptosis,GPCR/G Protein |
| Format | Solubility: H2O : 10 mg/mL (ultrasonic) |
| Grade | Clinical information: Launched |
| Purity | 99.88% |
| Molecular Formula | C52H72F3N13O14 |
| Molecular Weight | 1160.2 |
| CAS-Number | 2761969-44-0 |
| Storage Conditions | -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
