Givosiran
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-132610-1MG | 1 mg | 606,00 | Add | |
| HY-132610-5MG | 5 mg | 1'654,00 | Add | |
| HY-132610-10MG | 10 mg | 2'630,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Givosiran (ALN-AS1) is a small interfering RNA that targets hepatic aminolevulinate synthase 1 (ALAS1) messenger RNA. Givosiran downregulates ALAS1 mRNA and prevents accumulation of neurotoxic δ-aminolevulinic acid and porphobilinogen levels. Givosiran can be used for the research of acute intermittent porphyria[1][2].
| Category | Oligonucleotide |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | Neurological Disease, Epigenetics |
| Format | Solubility: 10 mM in H2O |
| Grade | Clinical information: Launched |
| Purity | 97.9% |
| Molecular Formula | C524H694F16N173O316P43S6 |
| CAS-Number | 1639325-43-1 |
| Storage Conditions | -20°C (Powder, protect from light) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
