IL-18R alpha, Mouse (326a.a, HEK293, His)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-P75847-2uG | 2 μg | 57,00 | Add | |
HY-P75847-10uG | 10 μg | 89,00 | Add | |
HY-P75847-50uG | 50 μg | 229,00 | Add | |
HY-P75847-100uG | 100 μg | 380,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor α (Rα) and β (Rβ) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kβ- inducing kinase, with subsequent activation of nuclear factor kβ[2]. IL-18R alpha inhibits the production of IFN-γ stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Mouse (326a.a, HEK293, His) is a recombinant protein with a His label that consists of 326 amino acids (M1-G326) and is produced by HEK293 cells.
Category | Protein |
Supplier | MedChem Express |
Regulatory Status | RUO |
Genebank | 16182(Gene_ID)Q61098/NP_032391.1 (K20... |
Purity | 98% |
Molecular Weight | 5575 |
Storage Conditions | Stored at -20°C for 2 years |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Blue Ice |
Material Safety Data Sheet | Download PDF |