NSC756093


Catalog Number Pack Size List Price* Promo Price* Quantity
HY-12929-1MG 1 mg 59,00 0,00 Add
HY-12929-5x1MG 1 mg * 5 114,00 0,00 Add
HY-12929-10MG 10 mg 177,00 109,80 Add
HY-12929-25MG 25 mg 339,00 210,20 Add

* CHF, excl. 8.1% VAT and shipping costs


Product Description

Promotion runs until 31.12.2026

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SU093
NSC756093 (SU093) is a GBP1:PIM1 interaction inhibitor. NSC756093 binds to GBP1-PIM1 with a Kd of 38 nM. NSC756093 suppresses proliferation, reduces migration, induces G1 phase cell-cycle arrest, and increases apoptotic cell death in ovarian cancer cells. NSC756093 reduces cellular proteasomal activity, induces accumulation of ubiquitinated proteins, and restrains tumor progression and lung metastasis in murine ovarian cancer xenograft models. NSC756093 increases sensitivity of prostate cancer cells to Docetaxel (HY-B0011) and sensitizes GBP1-overexpressing ovarian cancer cells to Paclitaxel (HY-B0015) . NSC756093 can be used for the research of prostate cancer and ovarian cancer[1][2][3][4].

Category Biochemicals
Supplier MedChem Express
Regulatory Status RUO
Research Field Cancer
Format Solubility: DMSO : 62.5 mg/mL (ultrasonic)
Grade Clinical information: No Development Reported
Purity 99.58%
Molecular Formula C20H19NO4
Molecular Weight 337.37
CAS-Number 1629908-92-4
Storage Conditions -20°C, 3 years; 4°C, 2 years (Powder)
Tech. Data Sheet View datasheet
Link To Supplier http://www.medchemexpress.com
Shipping Details Room Temperature
Material Safety Data Sheet Download PDF