Fmoc-His(3-Me)-OH
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
HY-W111226-50MG | 50 mg | 128,00 | Add | |
HY-W111226-100MG | 100 mg | 204,00 | Add | |
HY-W111226-250MG | 250 mg | 330,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel[1][2][3].
Category | Peptide |
Supplier | MedChem Express |
Regulatory Status | RUO |
Research Field | Cardiovascular Disease, Neuronal Signaling,s |
Format | Solubility: 10 mM in DMSO |
Grade | Clinical information: No Development Reported |
Purity | 98% |
Molecular Formula | C22H21N3O4 |
Molecular Weight | 391.42 |
CAS-Number | 252049-16-4 |
Storage Conditions | -20°C, 3 years; 4°C, 2 years (Powder) |
Tech. Data Sheet | View datasheet |
Link To Supplier | http://www.medchemexpress.com |
Shipping Details | Room Temperature |
Material Safety Data Sheet | Download PDF |