CD4 PE, ASR
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
4120022-50TST | 50 Test | 327,00 | Add | |
4120025-100TST | 100 Test | 531,00 | Add | |
4120022-FS | Free sample | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
Category | Antibody |
Supplier | Caprico Biotechnologies |
Application | FC |
Regulatory Status | RUO |
Host | Ms |
Clone Number | [SK3] |
Isotype | IgG1,k |
Crossreactivity | Cynomolgus, Hu, Rhesus |
Grade | ASR |
Conjugation | PE |
Storage Conditions | 2-8°C |
Link To Supplier | https://www.capricobio.com |
Shipping Details | 2-8°C |
Material Safety Data Sheet | Download PDF |