ARC19499
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| HY-153480-1ST | Get quote | Inquire |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
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ARC19499 is an aptamer that inhibits tissue factor pathway inhibitor (TFPI) , thereby enabling clot initiation and propagation via the extrinsic pathway. The core aptamer binds tightly and specifically to TFPI. ARC19499 blocks TFPI inhibition of both factor Xa and the TF/factor VIIa complex. ARC19499 corrects thrombin generation in hemophilia A and B plasma and restores clotting in FVIII-neutralized whole blood.
| Category | RNAi |
| Supplier | MedChem Express |
| Regulatory Status | RUO |
| Research Field | s, Metabolic Enzyme/Protease |
| Format | Solubility: H2O : ≥ 100 mg/mL |
| Grade | Clinical information: Phase 1 |
| Purity | 93.65% |
| CAS-Number | 1350667-54-7 |
| Storage Conditions | -20°C (Powder, sealed storage, away from moisture) |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | http://www.medchemexpress.com |
| Shipping Details | Blue Ice |
| Material Safety Data Sheet | Download PDF |
