CD49e (Integrin alpha 5) Monoclonal Antibody (P1D6), PE, eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
12-4900-42 | 100 Tests | 355,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: This P1D6 monoclonal antibody reacts with human CD49e, which is also known as integrin alpha 5. Integrins constitute a family of cell surface receptors that mediate adhesion between cells or between a cell and the extracellular matrix. These proteins are heterodimers consisting of two distinct subunits, alpha and beta. Integrin alpha 5 is expressed on thymocytes, T cells, monocytes, platelets, as well as early and activated B cells. Integrins are also expressed on non-hematopoietic and cancer cells. Integrin-mediated adhesion is regulated by changes in ligand affinity (or activation), cell shape, and integrin clustering and diffusion. Integrin alpha 5 undergoes post-translational cleavage in its extracellular domain to produce disulfide-linked light and heavy chains that associate with the common beta 1 subunit to form the fibronectin receptor. Studies have demonstrated the involvement of this integrin in cell adhesion, signaling, and apoptosis. The P1D6 monoclonal antibody has been reported to have blocking activity. Crossblocking studies indicate that P1D6 and eBioSAM-1 recognize a similar epitope. Applications Reported: This P1D6 antibody has been reported for use in flow cytometric analysis. Applications Tested: This P1D6 antibody has been pre-ti
Category | Antibody |
Supplier | ThermoFisher |
Application | FC |
Regulatory Status | RUO |
Host | Ms |
Clone Number | [P1D6] |
Genebank | ITGA5 |
Isotype | IgG3 |
Crossreactivity | Hu |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with 0.2% BSA and 0.09% sodium azide |
Concentration | 5 µL/Test |
Working Dilution | Flow Cytometry (5 µL (0.25 µg)/test) |
Purity | Affinity chromatography |
Conjugation | PE |
Storage Conditions | 4° C, store in dark, DO NOT FREEZE! |
Disclaimer | Alternative CatNo: 12490042 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |