CD2 Monoclonal Antibody (RM2-5), eBioscience™

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Product Description

Description: The RM2-5 monoclonal antibody reacts with the mouse CD2 molecule, an approximately 50-55 kDa cell surface receptor expressed by all mouse lymphocytes. Expression of the CD2 antigen in the mouse differs from that of the human in that B lineage cells in the mouse from the pre-B cell stage to mature B cells express CD2. CD2 is a ligand for CD48 in the mouse and is involved in adhesion and activation of T cells. Applications Reported: The RM2-5 antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining of frozen tissue sections. RM2-5 has also been reported in blocking of CD2 activity in in vitro functional assays. (Please use Functional Grade purified RM2-5, cat. 16-0021, in functional assays.). Applications Tested: The RM2-5 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater tha