CD3 Monoclonal Antibody (eBioG4.18 (G4.18)), eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
14-0030-85 | 500 µg | 312,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: The eBioG4.18 monoclonal antibody recognizes the rat CD3 protein. CD3 is a critical component of the T-cell receptor (TCR) and is a marker of the T-cell lineage. CD3 is a complex of several subunits and, upon binding of a TCR ligand, participates in transduction of signals from the TCR to the nucleus which results in a variety of cellular responses including transcription of IL-2 and clonal expansion. in vitro, immobilized G4.18 monoclonal antibody has been demonstrated to activate T cells, while soluble G4.18 inhibited allogeneic mixed-lymphocyte proliferative responses and cell-mediated cytotoxicity to allogeneic target cells. in vivo, G4.18 was demonstrated to induce long-term specific tolerance to an organ allograft. Applications Reported: This eBioG4.18 (G4.18) antibody has been reported for use in flow cytometric analysis, immunoprecipitation, immunoblotting (WB), and immunohistochemical staining. Applications Tested: This eBioG4.18 (G4.18) antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but ca
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Host | Ms |
Clone Number | [eBioG4.18 (G4.18)] |
Genebank | CD247 |
Isotype | IgG3,k |
Crossreactivity | Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with 0.09% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Flow Cytometry (0.5 µg/test), Western Blot (Assay-Dependent), Immunoprecipitation (Assay-Dependen... |
Purity | Affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: 14003085 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |