CD29 (Integrin beta 1) Monoclonal Antibody (eBioHMb1-1 (HMb1-1)), Functional Grade, eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
16-0291-85 | 500 µg | 464,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: The eBioHMb1-1 monoclonal antibody reacts with mouse and rat CD29 (integrin beta 1), a 110-120 kDa member of the beta integrin family expressed by leukocytes, endothelial, smooth muscle and epithelial cells. CD29 binds non-covalently with the alpha integrins CD49a-f to form the VLA-1 through VLA-6 complexes, as well as with CD51. These alpha-beta integrin heterodimers are capable of mediating a variety of cellular responses including adhesion, trafficking, proliferaton and differentiation. All integrins which include CD29 bind to extracellular matrix proteins including collagen, laminin, fibronectin and vitronectin, whereas some CD29-containing integrins can also interact with cellular receptors such as VCAM-1 and MadCAM-1. Applications Reported: This eBioHMb1-1 (HMb1-1) antibody has been reported for use in flow cytometric analysis. The HMb1-1 monoclonal antibody has been reported to block VLA-dependent cellular functions, including the adhesion of mouse tumor cell lines to extracellular matrix proteins, and splenic T-cell proliferation induced by anti-CD3 monoclonal antibody. Applications Tested: This eBioHMb1-1 (HMb1-1) antibody has been tested by flow cytometric analysis of mouse spleen, thymus and bone marrow cells. This can be used at less than
Category | Antibody |
Supplier | ThermoFisher |
Application | FC, N |
Regulatory Status | RUO |
Host | Hm |
Clone Number | [eBioHMb1-1 (HMb1-1)] |
Genebank | ITGB1 |
Isotype | IgG |
Crossreactivity | Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with no preservative |
Concentration | 1 mg/mL |
Working Dilution | Neutralization (Assay-Dependent), Flow Cytometry (1 µg/test), Functional Assay (Assay-Dependent) |
Purity | Affinity chromatography |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: 16029185 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |