CD339 (Jagged 1) Monoclonal Antibody (HMJ1-29), Functional Grade, eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
16-3391-85 | 500 µg | 455,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: This HMJ1-29 monoclonal antibody reacts with mouse Jagged-1, one of five type I transmembrane proteins that serves as a Notch receptor ligand. Upon binding the Notch receptor (e.g. Notch 1-4), Jagged-1 undergoes proteolytic cleavage, first by ADAM-family metalloproteases and then by gamma-secretase. The second cleavage event releases an intracellular fragment whose biological function remains controversial. Jagged-1 is expressed by thymic lymphoid and stromal cells, as well as macrophages and CD8+CD11c+ dendritic cells in the spleen. The HMJ1-29 antibody is reported to crossreact to rat. Applications Reported: This HMD1-5 antibody has been reported for use in functional assays. Applications Tested: This HMJ1-29 antibody has been tested by flow cytometric analysis of Jagged-1-transfected CHO cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 µm post-man
Category | Antibody |
Supplier | ThermoFisher |
Application | FA |
Regulatory Status | RUO |
Host | Hm |
Clone Number | [HMJ1-29] |
Genebank | JAG1 |
Isotype | IgG |
Crossreactivity | Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.2, with no preservative |
Concentration | 1 mg/mL |
Working Dilution | Functional Assay (Assay-Dependent) |
Purity | Affinity chromatography |
Storage Conditions | 4° C |
Disclaimer | Alternative CatNo: 16339185 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |