alpha Tubulin Monoclonal Antibody (B-5-1-2), Alexa Fluor™ 488
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
322588 | 100 µg | 680,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody reacts with all forms of alpha tubulin. The expected molecular weight is ~50.5 kDa. Reactivity is confirmed with NIH3T3 cells, rat brain, mouse testis, human Caco-2, HeLa3 and PtK23 cells. Excitation/Emission (nm) for this Alexa Fluor 488™-conjugated antibody: 495/519 Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown
Category | Antibody |
Supplier | ThermoFisher |
Application | ICC |
Regulatory Status | RUO |
Immunogen | Sarkosyl-resistant filament from sea urchin sperm axonemes |
Host | Ms |
Clone Number | [B-5-1-2] |
Genebank | TUBA1A |
Isotype | IgG1,k |
Crossreactivity | Hu, Ms, Rt, Sea urchin |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 4mg/mL BSA and 0.1% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Immunocytochemistry (2 µg/mL) |
Purity | Protein A |
Conjugation | Alexa Fluor 488 |
Storage Conditions | Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |