Synuclein alpha/beta Monoclonal Antibody (Syn 202)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 328200 | 100 µg | 664,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant human alpha- and beta-synuclein. |
| Host | Ms |
| Clone Number | [Syn 202] |
| Genebank | SNCA |
| Isotype | IgG2a |
| Crossreactivity | Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (1-3 µg/mL), Immunocytochemistry (1-2 µg/mL), Immunohistochemistry (Assay-dependent)... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: 32-8200 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
