Cytochrome C Monoclonal Antibody (6H2.B4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 338200 | 100 µg | 586,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
This antibody reacts with native Cytochrome C, but does not recognize denatured cytochrome C. The antibody recognizes a region in the vicinity of amino acid 62 of rat Cytochrome C. Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IP |
| Regulatory Status | RUO |
| Immunogen | Rat Cytochrome C. |
| Host | Ms |
| Clone Number | [6H2.B4] |
| Genebank | CYCS |
| Isotype | IgG1,k |
| Crossreactivity | Drosophila, Hu, Ms, Rb, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | ELISA (0.1-1 µg/mL), Immunoprecipitation (15 µg), Immunocytochemistry (5-20 µg/mL) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C |
| Disclaimer | Alternative CatNo: 33-8200 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
