Cytochrome C Monoclonal Antibody (7H8.2C12)
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
338500 | 200 µg | 590,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Cytochrome C is an electron transporting protein that resides within the intermembrane space of the mitochondria, where it plays a critical role in oxidative phosphorylation and the production of cellular ATP. Release of cytochrome C from the mitochondria to the cytosol is triggered by apoptotic stimuli. In the cytoplasm, the cytochrome C binds apoptotic protease activating factor which activates the apoptotic initiator procaspase 9. Cytosolic cytochrome C functions in the activation of caspase 3, an ICE family molecule that is a key effector of apoptosis.
Category | Antibody |
Supplier | ThermoFisher |
Application | WB |
Regulatory Status | RUO |
Immunogen | Equine Cytochrome c. |
Host | Ms |
Clone Number | [7H8.2C12] |
Genebank | CYCS |
Isotype | IgG2b,k |
Crossreactivity | Drosophila, Ho, Hu, Ms, Rb, Rt, Xenopus |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Western Blot (1:1,000) |
Purity | Affinity chromatography |
Conjugation | Unconjugated |
Storage Conditions | -20°C |
Disclaimer | Alternative CatNo: 33-8500 |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |