NFkB p65 Monoclonal Antibody (2A12A7)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 339900 | 100 µg | 600,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB P65 is also known as RelA (v-rel avian reticuloendotheliosis viral oncogene homolog A) and belongs to the Rel family of proteins. It is one of the two subunits of NF-kB (Nuclear factor kappa-light-chain-enhancer of activated B cells) that heterodimerizes with the other subunits p50 or p52. However, binding of TNF alpha to its cognate receptor phosphorylates IKK which in turn phosphorylates I kB allowing proteasomal degradation of I kB. It specifically plays a key role in transcription of immunoglobulin k (kappa) gene in mature B-lymphoid cells.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | ChIP, EL, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Recombinant protein (~175 amino acids) from the C-terminal portion of human NF-kappa-B (p65). |
| Host | Ms |
| Clone Number | [2A12A7] |
| Genebank | RELA |
| Isotype | IgG2a |
| Crossreactivity | Hu, Ms |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | ChIP Assay (3 µg/mL), Western Blot (0.5 - 1 µg/mL), Gel Shift (Assay-dependent), ELISA (Assay-dep... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: 33-9900 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
