Claudin 5 Monoclonal Antibody (4C3C2), Alexa Fluor™ 488
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
352588 | 100 µg | 628,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Reactivity has been confirmed with rat, human and mouse Claudin-5 using rat lung, mouse kidney, mouse small intestine, mouse lung homogenates, human colon tissue, and CACO-2 human cell line. This antibody reacts specifically with the ~ 22-24 kDa endogenous Claudin-5 protein. Excitation/Peak Emission (nm): 495/519 This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
Category | Antibody |
Supplier | ThermoFisher |
Application | EL, ICC, IHC, IP, WB |
Regulatory Status | RUO |
Immunogen | Synthetic peptide derived from the mouse Claudin-5 protein |
Host | Ms |
Clone Number | [4C3C2] |
Genebank | CLDN5 |
Isotype | IgG1 |
Crossreactivity | Hu, Ms, Rt |
Clonality | Mab |
Format | Liquid; PBS; pH 7.4, with 4mg/mL BSA and 0.1% sodium azide |
Concentration | 0.5 mg/mL |
Working Dilution | Western Blot (Assay-dependent), Immunoprecipitation (Assay-dependent), Immunocytochemistry (Assay... |
Purity | Protein A |
Conjugation | Alexa Fluor 488 |
Storage Conditions | 4° C |
Tech. Data Sheet | View datasheet |
Link To Supplier | https://www.thermofisher.com |
Material Safety Data Sheet | Download PDF |