COX1 Monoclonal Antibody (COX 111)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 358100 | 100 µg | 584,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
PTGS1 (COX1, Cyclooxygenase 1) is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, FC, ICC, IHC, WB |
| Regulatory Status | RUO |
| Immunogen | Ram testes. |
| Host | Ms |
| Clone Number | [COX 111] |
| Genebank | COX1 |
| Isotype | IgG2b,k |
| Crossreactivity | Hu, Ms, Sh, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunohistochemistry (Assay-dependent), Immunocytochemistry (2 µg/mL), Flow Cytometry (3-5 µg/1x1... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | -20°C |
| Disclaimer | Alternative CatNo: 35-8100 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Material Safety Data Sheet | Download PDF |
