Claudin 1 Monoclonal Antibody (2H10D10)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 374900 | 100 µg | 652,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates. This antibody is specific for the C-terminal region of the claudin-1 protein. On western blots, it identifies the target band at ~22 kDa. Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, IHC, IP, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins |
| Host | Ms |
| Clone Number | [2H10D10] |
| Genebank | CLDN1 |
| Isotype | IgG1 |
| Crossreactivity | Dg, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Western Blot (1-3 µg/mL), Immunohistochemistry (Frozen) (5-10 µg/mL), Immunoprecipitation (10 µg/... |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: 37-4900 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
