IDO Monoclonal Antibody (eyedio), Brilliant Violet™ 421, eBioscience™
Catalog Number | Pack Size | List Price* | Quantity | |
---|---|---|---|---|
404-9477-41 | 25 Tests | 140,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
Description: This eyedio monoclonal antibody reacts with human indoleamine-2,3-dioxygenase (IDO, INDO, IDO1), an intracellular enzyme that catalyzes the degradation of tryptophan to kynurenines. IDO is expressed in a wide variety of tissues and cells, including macrophages, plasmacytoid dendritic cells, and several cell lines. IDO can be induced in many different cell types by IFN gamma or other inflammatory stimuli. Expression of IDO in antigen presenting cells and tumors is thought to mediate immune suppression through depletion of this essential amino acid and/or by the creation of tryptophan metabolites that cause apoptosis of T cells and induction of regulatory T cells. Applications Reported: This eyedio antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This eyedio antibody has been pre-diluted and tested by intracellular staining followed by flow cytometric analysis of normal human peripheral blood cells using the Intracellular Fixation & Permeabilization Buffer Set (Product # 88-8824-00) and protocol. Please refer to "Staining Intracellular Antigens for Flow Cytometry, Protocol A: Two step protocol for intracellular (cytoplasmic) proteins" located at
Category
Antibody
Supplier
ThermoFisher
Application
FC
Regulatory Status
RUO
Host
Ms
Clone Number
[eyedio]
Genebank
IDO1
Isotype
IgG1,k
Crossreactivity
Hu
Clonality
Mab
Format
liquid; PBS; pH 7.2, with BSA and 0.09% sodium azide
Concentration
5 µL/Test
Working Dilution
Flow Cytometry (5 µL (0.125 µg)/test)
Purity
Affinity chromatography
Conjugation
Brilliant Violet 421
Storage Conditions
4° C, store in dark, DO NOT FREEZE!
Disclaimer
Alternative CatNo: 404947741
Tech. Data Sheet
View datasheet
Link To Supplier
https://www.thermofisher.com
Material Safety Data Sheet
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