EB1 Monoclonal Antibody (1A11/4)
| Catalog Number | Pack Size | List Price* | Quantity | |
|---|---|---|---|---|
| 412100 | 100 µg | 688,00 | Add |
* CHF, excl. 8.1% VAT and shipping costs
Product Description
EB1 family proteins are evolutionarily conserved proteins that bind microtubule plus-ends and centrosomes and regulate the dynamics and organization of microtubules. The MAPRE genes encode the EB1 family proteins. The human MAPRE genes MAPRE1, MAPRE2, and MAPRE3 code for EB1, RP1, and EBF3 proteins, respectively. EB1 family members appear to be expressed ubiquitously. The EB1 (MAPRE1) gene, at 20q11. 2, is fused to MLL in an adult patient with pro-B acute lymphoblastic leukemia. EB1 is a microtubule-associated protein that interacts with the colorectal adenomatous polyposis coli tumor-suppressor protein and plays important roles in regulating microtubule dynamics, cell polarity, and chromosome stability.
| Category | Antibody |
| Supplier | ThermoFisher |
| Application | EL, ICC, WB |
| Regulatory Status | RUO |
| Research Field | PROTEIN & CELL ANALYSIS |
| Immunogen | Recombinant protein encompassing the N-terminal domain of the human EB1 protein |
| Host | Ms |
| Clone Number | [1A11/4] |
| Genebank | MAPRE1 |
| Isotype | IgG2b,k |
| Crossreactivity | Dg, Hu, Ms, Rt |
| Clonality | Mab |
| Format | Liquid; PBS; pH 7.4, with 0.1% sodium azide |
| Concentration | 0.5 mg/mL |
| Working Dilution | Immunocytochemistry (Assay-dependent), Western Blot (1-3 µg/mL), ELISA (Assay-dependent) |
| Purity | Protein A |
| Conjugation | Unconjugated |
| Storage Conditions | Freezer (-5 to -30 C) |
| Disclaimer | Alternative CatNo: 41-2100 |
| Tech. Data Sheet | View datasheet |
| Link To Supplier | https://www.thermofisher.com |
| Shipping Details | Ambient |
| Material Safety Data Sheet | Download PDF |
